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原文連結
論文資訊
- 類型：已發表論文
- 日期：1997
摘要
Most HIV-1 infections of children result from mother-to-infant 傳播, which may occur perinatally or postnatally, as a consequence of breast feeding(1-8). In this study, the influence of maternal viral load on 傳播 of infection to infants from non-breast-feeding mothers was examined using samples of plasma and peripheral blood mononuclear cells (PBMCs) collected at several time points during pregnancy and the 6-month period after delivery. These samples were analyzed by several quantitative methods, including 病毒 cultures of PBMCs and polymerase chain reaction (PCR) assays for HIV-1 RNA in plasma and DNA in PBMCs. The risk of 傳播 increased slightly with a higher viral load, but 傳播 and non傳播 occurred over the entire range of values for each assay. No threshold... [text ended here...]
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