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原文連結
論文資訊
- 類型：已發表論文
- 日期：1998
摘要
There is considerable 遺傳 多樣性 among 病毒es of different subtypes (designated A to J) in the major group of human immunodeficiency 病毒 type 1 (HIV-1), the form of HIV that is dominant in the global 流行病學c(1-3). If available, HIV-1 sequences pre-dating the recognition of AIDS could be crucial in defining the time of origin and the subsequent 演化 of these 病毒es in humans. The oldest known case of HIV-1 infection was reported to be that of a sailor from Manchester who died of an AIDS-like illness in 1959 (refs 4-6); however, the authenticity of this case has not been confirmed(7,8). 遺傳 analysis of sequences from clinical materials obtained from 1971 to 1976 from members of a Norwegian family infected earlier than 1971 showed that they carried 病毒es of the HIV-1 outlier group(9,10), a variant form that
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