聖塔非研究所

摘要 In a prospective cohort study, clinical and biolo

1999 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 In a prospective cohort study, clinical and biologic factors that contribute to maternal child 傳播 of human immunodeficiency 病毒 type 1 (HIV 1) were studied, HIV infected pregnant women and…

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  • 類型:已發表論文
  • 日期:1999

摘要

In a prospective cohort study, clinical and biologic factors that contribute to maternal-child 傳播 of human immunodeficiency 病毒 type 1 (HIV-1) were studied, HIV-infected pregnant women and their infants were evaluated prospectively according to a standardized protocol. Of 204 evaluable women, 81% received zidovudine during their pregnancy. The infection rate among the 209 evaluable infants was 9.1%. By univariate analysis, histologic chorioamnionitis, prolonged rupture of membranes, and a history of genital warts were significantly associated with 傳播. Additional factors associated with 傳播 that approached significance included a higher maternal 病毒 load at delivery and the presence of cocaine in the urine. In a logistic regression model, histologic chorioamnionitis was the only independent pr

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