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原文連結
論文資訊
- 類型：已發表論文
- 日期：2002
摘要
遺傳 突變s that lead to undetectable or minimal changes in phenotypes are said to reveal redundant functions. Redundancy is common among phenotypes of higher organisms that experience low 突變 rates and small 族群 sizes. Redundancy is less common among organisms with high 突變 rates and large 族群s, or among the rapidly dividing cells of multicellular organisms. In these cases, one even observes the opposite tendency: a hypersensitivity to 突變, which we refer to as antiredundancy. In this paper we analyze the 演化ary dynamics of redundancy and antiredundancy. Assuming a cost of redundancy, we find that large 族群s will evolve antiredundant mechanisms for removing mutants and thereby bolster the robustness of wild-type 基因組s; whereas small 族群s will evolve redundancy to ensure that all individuals have a high
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