聖塔非研究所

摘要 We estimate parameters of a general isolation wit

2007 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 We estimate parameters of a general isolation with migration model using resequence data from mitochondrial DNA (mtDNA), the Y chromosome, and two loci on the X chromosome in samples of 2…

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  • 類型:已發表論文
  • 日期:2007

摘要

We estimate parameters of a general isolation-with-migration model using resequence data from mitochondrial DNA (mtDNA), the Y chromosome, and two loci on the X chromosome in samples of 25-50 individuals from each of 10 human 族群s. Application of a coalescent-based 馬可夫 chain 蒙地卡羅 technique allows simultaneous inference of divergence times, rates of gene flow, as well as changes in effective 族群 size. Results from comparisons between sub-Saharan African and Eurasian 族群s estimate that 1500 individuals founded the ancestral Eurasian 族群 similar to 40 thousand years ago (KYA). Furthermore, these small Eurasian founding 族群s appear to have grown much more dramatically than either African or Oceanian 族群s. Analyses of sub-Saharan African 族群s provide little evidence for a history, of 族群 bottlenecks an

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