本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2008
摘要
Background: Elucidating the architecture and dynamics of large scale 遺傳 regulatory 網絡s of cells is an important goal in systems biology. We study the system level dynamical properties of the 遺傳 網絡 of Escherichia coli that regulates its 代謝, and show how its design leads to 生物ly useful cellular properties. Our study uses the database (Covert et al., Nature 2004) containing 583 genes and 96 external metabolites which describes not only the 網絡 connections but also the Boolean rule at each gene node that controls the switching on or off of the gene as a function of its inputs. Results: We have studied how the 吸引子s of the Boolean dynamical system constructed from this database depend on the initial condition of the genes and on various environmental conditions corresponding to buffered minimal m
※ 此為已發表論文，全文需透過期刊付費取得