本頁只刊出中文翻譯與中文說明;英文原文請見下方原文連結。
原文連結
論文資訊
- 類型:已發表論文
- 日期:2008
摘要
In many infectious 疾病s, an unknown fraction of infections produce symptoms mild enough to go unrecorded, a fact that can seriously compromise the interpretation of 流行病學ological records. This is true for cholera, a pandemic 細菌l 疾病, where estimates of the ratio of asymptomatic to symptomatic infections have ranged from 3 to 100 (refs 1-5). In the absence of direct evidence, understanding of fundamental aspects of cholera 傳播, immunology and control has been based on assumptions about this ratio and about the immunological consequences of inapparent infections. Here we show that a model incorporating high asymptomatic ratio and rapidly waning immunity, with infection both from human and environmental sources, explains 50 yr of mortality data from 26 districts of Bengal, the pathogen's endemic
※ 此為已發表論文,全文需透過期刊付費取得