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原文連結
論文資訊
- 類型：已發表論文
- 日期：2008
摘要
The topology of metabolic 網絡s may provide important insights not only into the metabolic capacity of 物種, but also into the habitats in which they evolved. Here we introduce the concept of a metabolic 網絡's "seed set"-the set of compounds that, based on the 網絡 topology, are exogenously acquired-and provide a methodological framework to 計算ly infer the seed set of a given 網絡. Such seed sets form ecological "interfaces" between metabolic 網絡s and their surroundings, approximating the effective biochemical environment of each 物種. Analyzing the metabolic 網絡s of 478 物種 and identifying the seed set of each 物種, we present a comprehensive large-scale reconstruction of such predicted metabolic environments. The seed sets' composition significantly correlates with several basic properties characterizing
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