本頁只刊出中文翻譯與中文說明;英文原文請見下方原文連結。
原文連結
論文資訊
- 類型:已發表論文
- 日期:2009
摘要
Motivation: The RNA-RNA interaction problem (RIP) consists in finding the energetically optimal structure of two RNA molecules that bind to each other. The standard model allows secondary structures in both partners as well as additional base pairs between the two RNAs subject to certain restrictions that ensure that RIP is solvabale by a polynomial time dynamic programming algorithm. RNA-RNA binding, like RNA folding, is typically not dominated by the ground state structure. Instead, a large ensemble of alternative structures contributes to the interaction 熱力學s. Results: We present here an O(N-6) time and O(N-4) dynamics programming algorithm for computing the full partition function for RIP which is based on the combinatorial notion of 'tight structures'. Albeit equivalent to recent work
※ 此為已發表論文,全文需透過期刊付費取得