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原文連結
論文資訊
- 類型：已發表論文
- 日期：2009
摘要
Background: Schistosomes are trematode parasites of the phylum Platyhelminthes. They are considered the most important of the human helminth parasites in terms of morbidity and mortality. Draft 基因組 sequences are now available for Schistosoma mansoni and Schistosoma japonicum. Non-coding RNA (ncRNA) plays a crucial role in gene expression regulation, cellular function and defense, homeostasis, and pathogenesis. The 基因組-wide annotation of ncRNAs is a non-trivial task unless well-annotated 基因組s of closely related 物種 are already available. Results: A homology search for structured ncRNA in the 基因組 of S. mansoni resulted in 23 types of ncRNAs with conserved primary and secondary structure. Among these, we identified rRNA, snRNA, SL RNA, SRP, tRNAs and RNase P, and also possibly MRP and 7SK RNAs
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