摘要 The process of gene expression has material costs

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原文連結

• SFI 頁面

論文資訊

• 類型：已發表論文
• 日期：2009

摘要

The process of gene expression has material costs caused by the quantities of carbon, nitrogen, sulfur and phosphorus that are needed to make mRNAs and 蛋白質s. When any such chemical element is ecologically limiting, 突變s increasing these costs can reduce growth. Here, we ask if such 突變s are 'visible' to 自然選擇 in the yeast Saccharomyces cerevisiae. We find that 突變s causing small increases in expression and even single amino acid replacements can be subject to 自然選擇 on the basis of their material costs.

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