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原文連結
論文資訊
- 類型：已發表論文
- 日期：2010
摘要
At a locus subject to genomic imprinting, the expression pattern of an allele depends on its parent of origin. Typically, one allele is expressed while the other is transcriptionally silent, and 自然選擇 at the locus will be driven by the inclusive fitness of the active allele. For some aspects of phenotype, the relevant fitness function differs between maternally and paternally derived alleles, so that maternally and paternally expressed imprinted loci become involved in an intragenomic, interlocus conflict. Here I consider the consequences of such a conflict between loci with pleiotropic effects and show that phenotypes are driven away from their optimal values, resulting in a maladaptive, but selectively favored, 演化ary trajectory. The extent to which the 演化arily stable state departs from th
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