本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2010
摘要
Background: A metabolic genotype comprises all chemical reactions an organism can catalyze via enzymes encoded in its 基因組. A genotype is viable in a given environment if it is capable of producing all biomass components the organism needs to survive and reproduce. Previous work has focused on the properties of individual genotypes while little is known about how 基因組-scale metabolic 網絡s with a given function can vary in their reaction content. Results: We here characterize spaces of such genotypes. Specifically, we study metabolic genotypes whose phenotype is viability in minimal chemical environments that differ in their sole carbon sources. We show that regardless of the number of reactions in a metabolic genotype, the genotypes of a given phenotype typically form vast, connected, and uns
※ 此為已發表論文，全文需透過期刊付費取得