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原文連結
論文資訊
- 類型:已發表論文
- 日期:2010
摘要
Background: Inter-subtype recombinants dominate the HIV 流行病學cs in three geographical regions. To better understand the role of HIV recombinants in shaping the current HIV 流行病學c, we here present the results of a large-scale subtyping analysis of 9435 HIV-1 sequences that involve subtypes A, B, C, G, F and the 流行病學ologically important recombinants derived from three continents. Results: The circulating recombinant form CRF02_AG, common in West Central Africa, appears to result from recombination events that occurred early in the divergence between subtypes A and G, followed by additional recent recombination events that contribute to the breakpoint pattern defining the current recombinant lineage. This finding also corrects a recent claim that G is a recombinant and a descendant of CRF02, wh
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