聖塔非研究所

摘要 During development, the mammalian 大腦 differentiat

2010 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 During development, the mammalian 大腦 differentiates into specialized regions with distinct functional abilities. While many factors contribute to functional specialization, we explore the…

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  • 類型:已發表論文
  • 日期:2010

摘要

During development, the mammalian 大腦 differentiates into specialized regions with distinct functional abilities. While many factors contribute to functional specialization, we explore the effect of neuronal density on the development of neuronal interactions in vitro. Two types of cortical 網絡s, namely, dense and sparse with 50,000 and 12,500 total cells, respectively, are studied. Activation graphs that represent pairwise neuronal interactions are constructed using a competitive first response model. These graphs reveal that, during development in vitro, dense 網絡s form activation connections earlier than sparse 網絡s. Link 熵 analysis of dense 網絡 activation graphs suggests that the majority of connections between electrodes are reciprocal in nature. 資訊 theoretic measures reveal that early fun

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