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原文連結
論文資訊
- 類型：已發表論文
- 日期：2010
摘要
he design and evaluation of 流行病學ological control strategies is central to public health policy. While inverse problem methods are routinely used in many applications, this remains an area in which their use is relatively rare, although their potential impact is great. We describe methods particularly relevant to 流行病學ological modeling at the 族群 level. These methods are then applied to the study of pneumococcal 疫苗接種 strategies as a relevant example which poses many challenges common to other infectious 疾病s. We demonstrate that relevant yet typically unknown parameters may be estimated, and show that a calibrated model may used to assess implemented vaccine policies through the estimation of parameters if vaccine history is recorded along with infection and colonization 資訊. Finally, we show h
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