本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2010
摘要
Knowing 突變 rates and the molecular spectrum of spontaneous 突變s is important to understanding how the 遺傳 composition of viral 族群s evolves. Previous studies have shown that the rate of spontaneous 突變s for RNA 病毒es widely varies between 0.01 and 2 突變s per 基因組 and generation, with plant RNA 病毒es always occupying the lower side of this range. However, this peculiarity of plant RNA 病毒es is based on a very limited number of studies. Here we analyze the spontaneous 突變al spectrum and the 突變 rate of Tobacco etch poty病毒, a model system of positive sense RNA 病毒es. Our experimental setup minimizes the action of purifying selection on the 突變al spectrum, thus giving a picture of what types of 突變s are produced by the viral replicase. As expected for a neutral target, we found that transitions and nonsynon
※ 此為已發表論文，全文需透過期刊付費取得