摘要 Owed to their reduced size and low number of 蛋白質s

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原文連結

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論文資訊

• 類型：已發表論文
• 日期：2010

摘要

Owed to their reduced size and low number of 蛋白質s encoded, RNA 病毒es and other subviral pathogens are often considered as being 遺傳ally too simple. However, this structural simplicity also creates the necessity for viral RNA sequences to encode for more than one 蛋白質 and for 蛋白質s to carry out multiple functions, all together resulting in complex patterns of 遺傳 interactions. In this work we will first review the experimental studies revealing that the architecture of viral 基因組s is dominated by antagonistic interactions among loci. Second, we will also review 數學 models and provide a description of 計算 tools for the study of RNA 病毒 dynamics and 演化. As an application of these tools, we will finish this review article by analyzing a 隨機 bit-string model of in silico 病毒 replication. This model analyz

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