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原文連結
論文資訊
- 類型：已發表論文
- 日期：2010
摘要
We present a 貝氏 method for the reconstruction of pedigrees in clonal 族群s using co-dominant genomic markers such as microsatellites and single nucleotide polymorphisms (SNPs). The accuracy of the algorithm is demonstrated for simulated data. We show that the joint estimation of parameters of interest such as the rate of self- fertilization is possible with high accuracy even with marker panels of moderate power. Classical methods can only assign a very limited number of 統計ly significant parentages in this case and would therefore fail. 統計 confidence is estimated by 馬可夫 Chain 蒙地卡羅 (MCMC) sampling. The method is implemented in a fast and easy to use open source software that scales to large datasets with many thousand individuals.
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