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原文連結
論文資訊
- 類型：已發表論文
- 日期：2010
摘要
Background: Positions of spliceosomal introns are often conserved between remotely related genes. Introns that reside in non- conserved positions are either novel or remnants of frequent losses of introns in some 演化ary lineages. A recent gain of such introns is difficult to prove. However, introns verified as novel are needed to evaluate contemporary processes of intron gain. Results: We identified 25 unambiguous cases of novel intron positions in 31 Drosophila genes that exhibit near intron pairs (NIPs). Here, a NIP consists of an ancient and a novel intron position that are separated by less than 32 nt. Within a single gene, such closely-spaced introns are very unlikely to have coexisted. In most cases, therefore, the ancient intron position must have disappeared in favour of the novel o
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