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原文連結
論文資訊
- 類型：已發表論文
- 日期：2011
摘要
Genomic imprinting is the phenomenon in which the expression pattern of an allele depends on its parental origin. When maternally expressed and paternally expressed imprinted loci affect the same trait, the result is an arms race, with each locus under selection to increase its level of expression. This article develops a model of the deleterious consequences of this escalation, deriving from an increase in the variance in gene expression level, and resulting increase in phenotypic variance in the 族群. This phenomenon is referred to here as "conflict-induced decanalization." Modifiers that canalize gene expression are selectively favored, but these induce further escalation from both loci, resulting in a net increase in phenotypic variance and a reduction in 族群 mean fitness. This results in
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