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原文連結
論文資訊
- 類型：已發表論文
- 日期：2011
摘要
The relationships between cellular, structural and dynamical properties tumors have traditionally been studied separately. Here, we construct a quantitative, predictive theory of solid tumor growth, metabolic ate, vascularization and necrosis that the relationships between these properties. To accomplish this, we develop a comprehensive theory that the interface and integration of the tumor vascular 網絡 and resource supply with the cardiovascular system of our theory enables a quantitative understanding of how cells, tissues, and vascular 網絡s act together across pie scales by building on recent theoretical advances in modeling both healthy vasculature and the detailed processes angiogenesis and tumor growth. The theory explicitly relates tumor vascularization and growth to metabolic rate, a
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