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原文連結
論文資訊
- 類型：已發表論文
- 日期：2011
摘要
Background: Many important 演化ary 適應s originate in the modification of gene regulatory circuits to produce new gene activity phenotypes. How do evolving 族群s sift through an astronomical number of circuits to find circuits with new adaptive phenotypes? The answer may often involve phenotypic plasticity. Phenotypic plasticity allows a genotype to produce different - alternative - phenotypes after non-遺傳 perturbations that include gene expression noise, environmental change, or epi遺傳 modification. Results: We here analyze a well-studied model of gene regulatory circuits. A circuit's genotype encodes the regulatory interactions among circuit genes, and its phenotype corresponds to a stable gene activity pattern the circuit forms. For this model, we study how genotypes are arranged in genotype s
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