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原文連結
論文資訊
- 類型：已發表論文
- 日期：2011
摘要
Functional RNA elements can be embedded also within exonic sequences coding for functional 蛋白質s. While not uncommon in 病毒es, only a few examples of this type have been described in some detail for eukaryotic 基因組s. Here we use RNAz and RNAcode, two comparative genomics methods that measure signatures of stabilizing selection acting on RNA secondary structure and peptide sequence, resp., to survey the fruit fly 基因組s. We estimate that there might be on the order of 1000 loci that are subject to dual selection pressure. The used 基因組-wide screens also expose the limitations of the currently available methods. (C) 2011 Elsevier Masson SAS. All rights reserved.
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