聖塔非研究所

摘要 Genomic imprinting is the differential expression

2011 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 Genomic imprinting is the differential expression of an allele based on the parent of origin. Recent transcriptome wide evaluations of the number of imprinted genes reveal complex pattern…

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論文資訊

  • 類型:已發表論文
  • 日期:2011

摘要

Genomic imprinting is the differential expression of an allele based on the parent of origin. Recent transcriptome-wide evaluations of the number of imprinted genes reveal complex patterns of imprinted expression among developmental stages and cell types. Such data demand a comprehensive 演化ary framework in which to understand the effect of 自然選擇 on imprinted gene expression. We present such a framework for how asymmetries in demographic parameters and fitness effects can lead to the 演化 of genomic imprinting and place recent theoretical advances in this framework. This represents a modern interpretation of the kinship theory, is well suited to studying 族群s with complex 社會 interactions, and provides predictions which can be tested with forthcoming transcriptomic data. To understand the intric

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