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原文連結
論文資訊
- 類型：已發表論文
- 日期：2011
摘要
Teleost fishes have extra Hox gene clusters owing to shared or lineage-specific 基因組 duplication events in rayfinned fish (actinopterygian) phylogeny. Hence, extrapolating between 基因組 function of teleosts and human or even between different fish 物種 is difficult. We have sequenced and analyzed Hox gene clusters of the Senegal bichir (Polypterus senegalus), an extant representative of the most basal actinopterygian lineage. Bichir possesses four Hox gene clusters (A, B, C, D); 系統發育 analysis supports their orthology to the four Hox gene clusters of the gnathostome ancestor. We have generated a comprehensive database of conserved Hox noncoding sequences that include cartilaginous, lobe-finned, and ray-finned fishes (bichir and teleosts). Our analysis identified putative and known Hox cis-regula
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