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原文連結
論文資訊
- 類型：已發表論文
- 日期：2011
摘要
The tremendous 演化ary potential of RNA 病毒es allows them to thrive despite host defense mechanisms and endows them with properties such as 湧現, host switching, and virulence. The frequency of mutant 病毒es after an infectious process results from the interplay between the error rate of the viral replicase, from purifying mechanisms acting after transcription on aberrant RNAs, and from the amplification dynamics of 病毒 RNA positive (+) and negative (-) strands. Two extreme scenarios describing viral RNA amplification are the geometric growth, in which each RNA strand serves as template for the synthesis of complementary strands with the same efficiency, and the stamping machine, where a strand is reiteratively used as template to synthesize multiple copies of the complementary. The resulting 突變 f
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