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原文連結
論文資訊
- 類型：已發表論文
- 日期：2011
摘要
Understanding the 演化 of virulence for RNA 病毒es is essential for developing appropriate control strategies. Although it has been usually assumed that virulence is a consequence of within-host replication of the parasite, viral strains may be highly virulent without experiencing large accumulation as a consequence of immunopathological host responses. Using two strains of Tobacco etch poty病毒 (TEV) that show a negative relationship between virulence and accumulation rate, we first explored the 演化 of virulence and fitness traits during simple and mixed infections. Short-term 演化 experiments initiated with each strain independently confirmed the 遺傳 and 演化ary stability of virulence and viral load, although infectivity significantly increased for both strains. Second, competition experiments betwe
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