本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2012
摘要
A canalized genotype is robust to environmental or 遺傳 perturbations. Canalization is expected to result from stabilizing selection on a well-adapted phenotype. Decanalization, the loss of robustness, might follow periods of directional selection toward a new optimum. The 演化ary forces causing decanalization are still unknown, in part because it is difficult to determine the fitness effects of 突變s in 族群s of organisms with complex genotypes and phenotypes. Here, we report direct experimental measurements of robustness in a system with a simple genotype and phenotype, the catalytic activity of an RNA enzyme. We find that the robustness of a 族群 of RNA enzymes decreases during a period of directional selection in the laboratory. The decrease in robustness is primarily caused by the selective swe
※ 此為已發表論文，全文需透過期刊付費取得