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原文連結
論文資訊
- 類型：已發表論文
- 日期：2012
摘要
A 代謝 is a complex 網絡 of chemical reactions that converts sources of energy and chemical elements into biomass and other molecules. To design a 代謝 from scratch and to implement it in a synthetic 基因組 is almost within technological reach. Ideally, a synthetic 代謝 should be able to synthesize a desired spectrum of molecules at a high rate, from multiple different nutrients, while using few chemical reactions, and producing little or no waste. Not all of these properties are achievable simultaneously. We here use a recently developed technique to create random metabolic 網絡s with pre-specified properties to quantify trade-offs between these and other properties. We find that for every additional molecule to be synthesized a 網絡 needs on average three additional reactions. For every additional carb
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