聖塔非研究所

摘要 Background: Transcription 網絡s define the core of

2012 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 Background: Transcription 網絡s define the core of the regulatory machinery of cellular life and are largely responsible for 資訊 processing and decision making. At the small scale, interacti…

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  • 類型:已發表論文
  • 日期:2012

摘要

Background: Transcription 網絡s define the core of the regulatory machinery of cellular life and are largely responsible for 資訊 processing and decision making. At the small scale, interaction motifs have been characterized based on their abundance and some seemingly general patterns have been described. In particular, the abundance of different feed-forward loop motifs in gene regulatory 網絡s displays systematic biases towards some particular topologies, which are much more common than others. The causative process of this pattern is still matter of debate. Results: We analyzed the entire motif-function landscape of the feed-forward loop using the formalism developed in a previous work. We evaluated the probabilities to implement possible functions for each motif and found that the kurtosis o

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