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原文連結
論文資訊
- 類型：已發表論文
- 日期：2012
摘要
Gilbert, Rossini, and Shankarappa (2005, Biometrics 61, 106-117) present four U-statistic based tests to compare 遺傳 多樣性 between different samples. The proposed tests improved upon previously used methods by accounting for the correlations in the data. We find, however, that the same correlations introduce an unacceptable bias in the sample estimators used for the variance and covariance of the inter-sequence 遺傳 distances for modest sample sizes. Here, we compute unbiased estimators for these and test the resulting improvement using simulated data. We also show that, contrary to the claims in Gilbert et al., it is not always possible to apply the Welch-Satterthwaite approximate t-test, and we provide explicit formulas for the degrees of freedom to be used when, on the other hand, such appro
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