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原文連結
論文資訊
- 類型：已發表論文
- 日期：2012-09-28
摘要
In this review we provide an overview of various bioinformatics methods and tools for the analysis of metazoan mitochondrial 基因組s. We compare available dedicated databases and present current tools for accurate 基因組 annotation, identification of 蛋白質 coding genes, and determination of tRNA and rRNA models. We also evaluate various tools and models for 系統發育 tree inference using gene order or sequence based data. As for gene order based methods, we compare rearrangement based and gene cluster based methods for gene order rearrangement analysis. As for sequence based methods, we give special emphasis to substitution models or data treatment that reduces certain systematic biases that are typical for metazoan mito基因組s such as within 基因組 and/or among lineage compositional heterogeneity.
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