聖塔非研究所

摘要 A drawback of recent antiviral therapies based on

2013 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 A drawback of recent antiviral therapies based on the transgenic expression of artificial microRNAs (amiRs) is the ease with which 病毒es generate escape 突變s. Here, we show two alternative …

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  • 類型:已發表論文
  • 日期:2013

摘要

A drawback of recent antiviral therapies based on the transgenic expression of artificial microRNAs (amiRs) is the ease with which 病毒es generate escape 突變s. Here, we show two alternative strategies for improving the effectiveness of resistance in plants. First, we expressed two amiRs complementary to independent targets in the viral 基因組, and second, we designed amiRs complementary to highly conserved RNA motifs in the viral 基因組.

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