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原文連結
論文資訊
- 類型：已發表論文
- 日期：2013
摘要
Healthy vasculature exhibits a hierarchical branching structure in which, on average, vessel radius and length change systematically with branching order. In contrast, tumor vasculature exhibits less hierarchy and more variability in its branching patterns. Although differences in vasculature have been highlighted in the literature, there has been very little quantification of these differences. 碎形 analysis is a natural tool for comparing tumor and healthy vasculature, especially because it has already been used extensively to model healthy tissue. In this paper, we provide a 碎形 analysis of existing vascular data, and we present a new 數學 framework for predicting tumor growth trajectories by coupling: (1) the 碎形 geometric properties of tumor vascular 網絡s, (2) metabolic properties of tumor c
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