聖塔非研究所

摘要 The cellular multiplicity of infection (MOI) is a

2013 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 The cellular multiplicity of infection (MOI) is a key parameter for describing the interactions between virions and cells, predicting the dynamics of mixed genotype infections, and unders…

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論文資訊

  • 類型:已發表論文
  • 日期:2013

摘要

The cellular multiplicity of infection (MOI) is a key parameter for describing the interactions between virions and cells, predicting the dynamics of mixed-genotype infections, and understanding 病毒 演化. Two recent studies have reported in vivo MOI estimates for Tobacco mosaic 病毒 (TMV) and Cauliflower mosaic 病毒 (CaMV), using sophisticated approaches to measure the distribution of two 病毒 variants over host cells. Although the experimental approaches were similar, the studies employed different definitions of MOI and estimation methods. Here, new model-selection-based methods for calculating MOI were developed. Seven alternative models for predicting MOI were formulated that incorporate an increasing number of parameters. For both datasets the best-supported model included spatial segregation

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