聖塔非研究所

摘要 The distribution of variation in a quantitative t

2013-12-05 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 The distribution of variation in a quantitative trait and its underlying distribution of genotypic 多樣性 can both be shaped by stabilizing and directional selection. Understanding either di…

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  • 類型:已發表論文
  • 日期:2013-12-05

摘要

The distribution of variation in a quantitative trait and its underlying distribution of genotypic 多樣性 can both be shaped by stabilizing and directional selection. Understanding either distribution is important, because it determines a 族群's response to 自然選擇. Unfortunately, existing theory makes conflicting predictions about how selection shapes these distributions, and very little pertinent experimental evidence exists. Here we study a simple 遺傳 system, an evolving RNA enzyme (ribozyme) in which a combination of high throughput genotyping and measurement of a biochemical phenotype allow us to address this question. We show that directional selection, compared to stabilizing selection, increases the genotypic 多樣性 of an evolving ribozyme 族群. In contrast, it leaves the variance in the phenoty

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