聖塔非研究所

摘要 Gene duplication is important in 演化, because it p

2014-02-04 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 Gene duplication is important in 演化, because it provides new raw material for 演化ary 適應s. Several existing hypotheses about the causes of duplicate retention and diversification differ in …

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論文資訊

  • 類型:已發表論文
  • 日期:2014-02-04

摘要

Gene duplication is important in 演化, because it provides new raw material for 演化ary 適應s. Several existing hypotheses about the causes of duplicate retention and diversification differ in their emphasis on gene dosage, subfunctionalization, and neofunctionalization. Little experimental data exist on the relative importance of gene expression changes and changes in coding regions for the 演化 of duplicate genes. Furthermore, we do not know how strongly the environment could affect this importance. To address these questions, we performed 演化 experiments with the TEM-1 beta lactamase gene in Escherichia coli to study the initial stages of duplicate gene 演化 in the laboratory. We mimicked tandem duplication by inserting two copies of the TEM-1 gene on the same plasmid. We then subjected these copi

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