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原文連結
論文資訊
- 類型:已發表論文
- 日期:2014-04-02
摘要
The 基因組 of most prokaryotes gives rise to surprisingly complex transcriptomes, comprising not only 蛋白質-coding mRNAs, often organized as operons, but also harbors dozens or even hundreds of highly structured small regulatory RNAs and unexpectedly large levels of anti-sense transcripts. Comprehensive surveys of prokaryotic transcriptomes and the need to characterize also their non-coding components is heavily dependent on 計算 methods and workflows, many of which have been developed or at least adapted specifically for the use with 細菌l and archaeal data. This review provides an overview on the state-of-the-art of RNA bioinformatics focusing on applications to prokaryotes.
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