聖塔非研究所

摘要 Background: A 代謝 can evolve through changes in it

2014-04-23 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 Background: A 代謝 can evolve through changes in its biochemical reactions that are caused by processes such as horizontal gene transfer and gene deletion. While such changes need to preser…

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  • 類型:已發表論文
  • 日期:2014-04-23

摘要

Background: A 代謝 can evolve through changes in its biochemical reactions that are caused by processes such as horizontal gene transfer and gene deletion. While such changes need to preserve an organism's viability in its environment, they can modify other important properties, such as a 代謝's maximal biomass synthesis rate and its robustness to 遺傳 and environmental change. Whether such properties can be modulated in 演化 depends on whether all or most viable 代謝s - those that can synthesize all essential biomass precursors - are connected in a space of all possible 代謝s. Connectedness means that any two viable 代謝s can be converted into one another through a sequence of single reaction changes that leave viability intact. If the set of viable 代謝s is disconnected and highly fragmented, then histo

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