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原文連結
論文資訊
- 類型：已發表論文
- 日期：2014-11-27
摘要
How multicellular life forms evolved from unicellular ones constitutes a major problem in our understanding of the 演化 of our biosphere. A recent set of experiments involving yeast cell 族群s have shown that selection for faster sedimenting cells leads to the appearance of stable aggregates of cells that are able to split into smaller clusters. It was suggested that the observed 演化ary patterns could be the result of evolved programmes affecting cell death. Here, we show, using a simple model of cell-cell interactions and evolving adhesion rates, that the observed patterns in cluster size and localized mortality can be easily interpreted in terms of waste accumulation and toxicity-driven apoptosis. This simple mechanism would have played a key role in the early 演化 of multicellular life forms b
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