摘要 In finite 族群s, an allele disappears or reaches fi

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論文資訊

• 類型：已發表論文
• 日期：2015

摘要

In finite 族群s, an allele disappears or reaches fixation due to two main forces, selection and drift. Selection is generally thought to accelerate the process: a selected 突變 will reach fixation faster than a neutral one, and a disadvantageous one will quickly disappear from the 族群. We show that even in simple diploid 族群s, this is often not true. Dominance and recessivity unexpectedly slow down the 演化ary process for weakly selected alleles. In particular, slightly advantageous dominant and mildly deleterious recessive 突變s reach fixation slightly more slowly than neutral ones (at most 5%). This phenomenon determines 遺傳 signatures opposite to those expected under strong selection, such as increased instead of decreased 遺傳 多樣性 around the selected site. Furthermore, we characterize a new phenome

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