摘要 The human microbiome represents a vastly complex

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原文連結

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論文資訊

• 類型：已發表論文
• 日期：2015

摘要

The human microbiome represents a vastly complex ecosystem that is tightly linked to many host-related processes and that directly impact human health. To date, however, most studies have focused on characterizing the composition of the microbiome in health and in 疾病 and on comparative analyses, and relatively little effort has been directed at studying and modeling the microbiome as an integrated and comprehensive 生物 system. In this talk, I will highlight the pressing need for the development of predictive system-level models of the microbiome and discuss potential 計算 frameworks for metagenomic-based modeling of this microbial system. I will describe several preliminary attempts at constructing such models at the cellular, ecological and supra-organismal levels, accounting for the complex

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