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原文連結
論文資訊
- 類型：已發表論文
- 日期：2015-01-20
摘要
It is extremely likely that the malaria vaccines currently in development will be used in conjunction with treated bednets and other forms of malaria control. The interaction of different intervention methods is at present poorly understood in a 疾病 such as malaria where immunity is more complex than for other pathogens that have been successfully controlled by 疫苗接種. Here we develop a general 數學 model of malaria 傳播 to examine the interaction between 疫苗接種 and bednets. Counterintuitively, we find that the frailty of malaria immunity will potentially cause both synergistic and antagonistic interactions between 疫苗接種 and the use of bednets. We explore the conditions that create these tensions, and outline strategies that minimize their detrimental impact. Our analysis specifically considers the
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