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原文連結
論文資訊
- 類型：已發表論文
- 日期：2015-01-29
摘要
Background. To combat the 2014-2015 Ebola 病毒 疾病 (EVD) 流行病學c in West Africa, the World Health Organization urged the rapid evaluation of convalescent whole blood (CWB) and plasma (CP) transfusion therapy. However, the feasibility and likely impacts of broad implementation of transfusions are yet unknown. Methods. We extended an Ebola 病毒 傳播 model published by the Centers for 疾病 Control and Prevention to include hospital-based convalescent donations and transfusions. Using recent 流行病學ological estimates for EVD in Liberia and assuming that convalescent transfusions reduce the case-fatality rate to 12.5% (range, 7.5%-17.5%), we projected the impacts of a countrywide ramp-up of transfusion therapy. Results. Under the 10% case-hospitalization rate estimated for Liberia in September 2014, large-sc
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