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原文連結
論文資訊
- 類型：已發表論文
- 日期：2015-02-09
摘要
Inducible nitric oxide synthase (iNOS) is an enzyme that plays a key role in intracellular 免疫 response against respiratory infections. Since various 物種 of nonhuman primates exhibit different levels of susceptibility to infectious respiratory 疾病s, and since variation in regulatory regions of genes is thought to play a key role in expression levels of genes, two candidate regulatory regions of iNOS were mapped, sequenced, and compared across five 物種 of nonhuman primates: African green monkeys (Chlorocebus sabaeus), pig-tailed macaques (Macaca nemestrina), cynomolgus macaques (Macaca fascicularis), Indian rhesus macaques (Macaca mulatta), and Chinese rhesus macaques (Macaca mulatta). In addition, we conducted an in silica analysis of the transcription factor binding sites associated with 遺傳 v
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