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原文連結
論文資訊
- 類型：已發表論文
- 日期：2015-08-19
摘要
Background: Despite their abundance, unspliced EST data have received little attention as a source of 資訊 on non-coding RNAs. Very little is know, therefore, about the genomic distribution of unspliced non-coding transcripts and their relationship with the much better studied regularly spliced products. In particular, their 演化 has remained virtually unstudied. Results: We systematically study the evidence on unspliced transcripts available in EST annotation tracks for human and mouse, comprising 104,980 and 66,109 unspliced EST clusters, respectively. Roughly one third of these are located totally inside introns of known genes (TINs) and another third overlaps exonic regions (PINs). Eleven percent are "intergenic", far away from any annotated gene. Direct evidence for the independent transc
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