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原文連結
論文資訊
- 類型：已發表論文
- 日期：2015-10-09
摘要
Cells are complex machines capable of processing 資訊 by means of an entangled 網絡 of molecular interactions. A crucial component of these decision-making systems is the presence of memory and this is also a specially relevant target of engineered synthetic systems. A classic example of memory devices is a 1-bit memory element known as the flip-flop. Such system can be in principle designed using a single-cell implementation, but a direct mapping between standard circuit design and a living circuit can be cumbersome. Here we present a novel 計算 implementation of a 1-bit memory device using a reliable multicellular design able to behave as a set reset flip-flop that could be implemented in yeast cells. The dynamics of the proposed synthetic circuit is investigated with a 數學 model using 生物ly-mea
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