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原文連結
論文資訊
- 類型:已發表論文
- 日期:2016
摘要
A long-standing observation in 演化ary virology is that RNA 病毒 族群s are highly polymorphic, composed by a mixture of genotypes whose abundances in the 族群 depend on complex interaction between fitness differences, 突變al coupling and 遺傳漂變. It was shown long ago, though in cell cultures, that most of these genotypes had lower fitness than the 族群 they belong, an observation that explained why single-virion passages turned on Muller's ratchet while very large 族群 passages resulted in fitness increases in novel environments. Here we report the results of an experiment specifically designed to evaluate in vivo the fitness differences among the subclonal components of a clonal 族群 of the plant RNA 病毒 tobacco etch poty病毒 (TEV). Over 100 individual 生物 subclones from a TEV clonal 族群 well adapted to the nat
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