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原文連結
論文資訊
- 類型：已發表論文
- 日期：2016-02-01
摘要
Background: The 基因組s of plant 病毒es have limited coding capacity, and to complete their infectious cycles, viral factors must target, direct or indirectly, many host elements. However, the interaction 網絡s between 病毒es and host factors are poorly understood. The genus Poty病毒 is the largest group of plus-strand RNA 病毒es infecting plants. Potyviral nuclear inclusion a (NIa) plays many roles during infection. NIa is a poly蛋白質 consisting of two domains, viral 蛋白質 基因組-linked (VPg) and protease (NIaPro), separated by an inefficiently utilized self-proteolytic site. To gain insights about the interaction between potyviral NIa and the host cell during infection, we constructed Tobacco etch 病毒 (TEV, genus Poty病毒) infectious clones in which the VPg or the NIaPro domains of NIa were tagged with the aff
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